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olivLaw · US equity research

Takeda Pharmaceutical Company Limited TAK

Pharmaceutical Preparations · SIC 2834

21.06USD+1.49% · 1 dayClose 04 Nov 2026

Takeda is a global research-driven biopharmaceutical company focused on gastrointestinal and inflammation, neuroscience, oncology, and plasma-derived therapies. In fiscal 2026 revenue reached 4505.7 billion JPY, and the company is in a transition period, with new launches and late-stage pipeline programs set against loss of exclusivity on important products.

The AI analysis may be outdated: new filings came after its sources (see the «AI analysis» section).

At the close of 04 Nov 2026, Takeda Pharmaceutical Company Limited (TAK) stock was 21.06 USD (+1.49% on the day), with beta 0.16, 52-week range 13.59–21.06 USD.

Data as of · AI analysis dated · Source: SEC filings and closing prices, computed by olivLaw.

Market cap
unavailable
shares as of 31 Mar 2020
P/E (TTM)
unavailable
Diluted EPS TTM 67.23 · TTM to 31 Mar 2025
E/P (TTM)
unavailable
TTM to 31 Mar 2025
Dividend yield
unavailable
Beta (2y)
0.16
Volatility (1y) 21%
52-week range
13.5921.06

Price history

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Technical reading

RSI (14)
71.3
overbought (≥ 70)
Bollinger (20, 2)
18.27 – 21.45
in the upper half of the band · %B 0.88 · band width 16.0%
SMA 50 / 200
19.00 / 17.60
uptrend (price > SMA50 > SMA200)
MACD (12, 26, 9)
0.60 / 0.52
MACD above signal

Indicators describe past prices; on their own they do not predict direction. On our history the RSI ≤ 40 filter added no return (see the signals methodology).

Performance

CompanyS&P 500vs S&P 500Vertical median
1 month+18.2%−1.1%+19.3 pp—
3 months+26.0%−0.5%+26.4 pp—
6 months+26.0%+4.4%+21.6 pp—
Year to date+35.1%+12.3%+22.8 pp—
1 year+55.3%+13.5%+41.8 pp—
3 years+50.3%+76.4%−26.1 pp—
5 years+47.8%+63.7%−15.9 pp—
Max drawdown (1y)
−20.1%
23 Feb 2026 → 03 Jun 2026
Max drawdown (5y)
−26.4%
09 May 2023 → 21 Jun 2024
Compound annual growth (5y)
+8.1%
S&P 500 +10.4%

Price returns, dividends excluded.

Quarterly results

ESEF annual reports carry no quarters: the results are annual (below).

E/P over time

the price (USD) and the reports are in different currencies

E/P = trailing-12-month diluted EPS / price at quarter end. E/P is the inverse of P/E and stays defined when earnings are negative.

Fiscal years

Fiscal year20182019202020212022202320242025
Revenue1,770.5 bn2,097.2 bn3,291.2 bn3,197.8 bn3,569.0 bn4,027.5 bn4,263.8 bn4,581.6 bn
Revenue YoY+2.2%+18.5%+56.9%−2.8%+11.6%+12.8%+5.9%+7.5%
Net income186.9 bn135.2 bn44.2 bn376.0 bn230.1 bn317.0 bn144.1 bn107.9 bn
Net income YoY+62.6%−27.7%−67.3%+749.9%−38.8%+37.8%−54.6%−25.1%
Diluted EPS237.56139.8228.25238.96145.87201.9491.1667.23
Diluted EPS YoY+62.4%−41.1%−79.8%+745.9%−39.0%+38.4%−54.9%−26.3%
net %10.6%6.4%1.3%11.8%6.4%7.9%3.4%2.4%
Free cash flow310.8 bn250.8 bn542.7 bn899.7 bn999.9 bn836.5 bn540.9 bn856.4 bn

Reported results vs expectations

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Balance sheet & financial health

Fiscal year 2025 · 31 Mar 2025

Cash
385.1 bn JPY
Financial debt
3,966.3 bn JPY
Net debt
3,581.2 bn JPY
Equity
6,936.0 bn JPY
Total assets
14,248.3 bn JPY
Debt / equity
0.57x
Current ratio
1.01x
ROE
1.5%
ROA
0.7%
FCF margin
18.7%

Financial statements (source on every figure)

Revenue and net income (JPY)

Margins

Income statement · JPY

Revenue
2023
4,027.5 bn
2024
4,263.8 bn
2025
4,581.6 bn

SEC (XBRL)· 25 Jun 2025verified

Cost of revenue
2023
1,244.1 bn
2024
1,426.7 bn
2025
1,580.2 bn

SEC (XBRL)· 25 Jun 2025verified

Gross profit
2023
2,783.4 bn ≈
2024
2,837.1 bn ≈
2025
3,001.3 bn ≈

SEC (XBRL)· 25 Jun 2025derived

Research & development
2023
633.3 bn
2024
729.9 bn
2025
730.2 bn

SEC (XBRL)· 25 Jun 2025verified

Operating income
2023
490.5 bn
2024
214.1 bn
2025
342.6 bn

SEC (XBRL)· 25 Jun 2025verified

Depreciation & amortisation
2023
664.4 bn
2024
728.0 bn
2025
761.4 bn

SEC (XBRL)· 25 Jun 2025verified

EBITDA
2023
1,154.9 bn ≈
2024
942.1 bn ≈
2025
1,104.0 bn ≈

SEC (XBRL)· 25 Jun 2025derived

Interest expense
2023
169.7 bn
2024
219.9 bn
2025
210.1 bn

SEC (XBRL)· 25 Jun 2025verified

Pre-tax income
2023
375.1 bn
2024
52.8 bn
2025
175.1 bn

SEC (XBRL)· 25 Jun 2025verified

Income tax
2023
58.1 bn
2024
-91.4 bn
2025
66.9 bn

SEC (XBRL)· 25 Jun 2025verified

Net income
2023
317.0 bn
2024
144.1 bn
2025
107.9 bn

SEC (XBRL)· 25 Jun 2025verified

Diluted EPS
2023
201.94
2024
91.16
2025
67.23

SEC (XBRL)· 25 Jun 2025verified

Weighted average diluted shares
2023
1.6 bn
2024
1.6 bn
2025
1.6 bn

SEC (XBRL)· 25 Jun 2025verified

Dividend per share
2023
—
2024
—
2025
—

SEC (XBRL)· 24 Jun 2020derived

Balance sheet · JPY

Cash
2023
533.5 bn
2024
457.8 bn
2025
385.1 bn

SEC (XBRL)· 25 Jun 2025verified

Receivables
2023
649.4 bn
2024
668.4 bn
2025
709.5 bn

SEC (XBRL)· 25 Jun 2025verified

Inventories
2023
986.5 bn
2024
1,209.9 bn
2025
1,217.3 bn

SEC (XBRL)· 25 Jun 2025verified

Current assets
2023
2,398.0 bn
2024
2,558.6 bn
2025
2,521.2 bn

SEC (XBRL)· 25 Jun 2025verified

Property, plant & equipment, net
2023
1,691.2 bn
2024
—
2025
—

SEC (XBRL)· 28 Jun 2023verified

Goodwill
2023
4,790.7 bn
2024
5,410.1 bn
2025
5,324.4 bn

SEC (XBRL)· 25 Jun 2025verified

Intangibles (excl. goodwill)
2023
4,269.7 bn
2024
4,274.7 bn
2025
3,631.6 bn

SEC (XBRL)· 25 Jun 2025verified

Total assets
2023
13,957.8 bn
2024
15,108.8 bn
2025
14,248.3 bn

SEC (XBRL)· 25 Jun 2025verified

Accounts payable
2023
649.2 bn
2024
547.5 bn
2025
475.5 bn

SEC (XBRL)· 25 Jun 2025verified

Long-term debt
2023
4,042.7 bn
2024
4,476.5 bn
2025
3,966.3 bn

SEC (XBRL)· 25 Jun 2025verified

Current liabilities
2023
2,481.9 bn
2024
2,313.1 bn
2025
2,506.5 bn

SEC (XBRL)· 25 Jun 2025verified

Total liabilities
2023
7,603.1 bn
2024
7,834.8 bn
2025
7,312.4 bn

SEC (XBRL)· 25 Jun 2025verified

Equity
2023
6,354.7 bn
2024
7,274.0 bn
2025
6,936.0 bn

SEC (XBRL)· 25 Jun 2025verified

Shares outstanding at year end
2023
—
2024
—
2025
—

SEC (XBRL)· 24 Jun 2020verified

Cash flow · JPY

Operating cash flow
2023
977.2 bn
2024
716.3 bn
2025
1,057.2 bn

SEC (XBRL)· 25 Jun 2025verified

Capex
2023
140.7 bn
2024
175.4 bn
2025
200.8 bn

SEC (XBRL)· 25 Jun 2025verified

Free cash flow
2023
836.5 bn ≈
2024
540.9 bn ≈
2025
856.4 bn ≈

SEC (XBRL)· 25 Jun 2025derived

Investing cash flow
2023
-607.1 bn
2024
-463.9 bn
2025
-367.1 bn

SEC (XBRL)· 25 Jun 2025verified

Financing cash flow
2023
-709.1 bn
2024
-354.4 bn
2025
-751.4 bn

SEC (XBRL)· 25 Jun 2025verified

Dividends paid
2023
279.4 bn
2024
287.2 bn
2025
302.5 bn

SEC (XBRL)· 25 Jun 2025verified

Share repurchases
2023
26.9 bn
2024
2.3 bn
2025
51.9 bn

SEC (XBRL)· 25 Jun 2025verified

Computed indicators

Growth

Revenue growth (YoY)
7.5%
computed by olivLawFY 2025
Revenue CAGR 3Y
8.7%
computed by olivLawFY 2022 → FY 2025
Revenue CAGR 5Y
6.8%
computed by olivLawFY 2020 → FY 2025
EBIT growth (YoY)
60.0%
computed by olivLawFY 2025
Net income growth (YoY)
-25.1%
computed by olivLawFY 2025
Net income CAGR 3Y
-22.3%
computed by olivLawFY 2022 → FY 2025
Net income CAGR 5Y
19.5%
computed by olivLawFY 2020 → FY 2025
EPS growth (YoY)
-26.3%
computed by olivLawFY 2025
EPS CAGR 3Y
-22.8%
computed by olivLawFY 2022 → FY 2025
EPS CAGR 5Y
18.9%
computed by olivLawFY 2020 → FY 2025
FCF growth (YoY)
58.3%
computed by olivLawFY 2025

Profitability

Gross margin
65.5%
computed by olivLawFY 2025
EBITDA margin
24.1%
computed by olivLawFY 2025
EBIT margin
7.5%
computed by olivLawFY 2025
Net margin
2.4%
computed by olivLawFY 2025
FCF margin
18.7%
computed by olivLawFY 2025

Returns

ROE
1.5%
computed by olivLawFY 2025 · balance sheet at 31 Mar 2025
ROA
0.7%
computed by olivLawFY 2025 · balance sheet at 31 Mar 2025
ROIC
1.9%
computed by olivLawFY 2025 · balance sheet at 31 Mar 2025
ROCE
2.9%
computed by olivLawFY 2025 · balance sheet at 31 Mar 2025
Payout ratio (EPS)
unavailable
input data missing
Payout ratio (FCF)
35.3%
computed by olivLawFY 2025

Balance sheet

Net debt
3,581.2 bn JPY
computed by olivLawbalance sheet at 31 Mar 2025
Net debt / EBITDA
3.2x
computed by olivLawFY 2025 · balance sheet at 31 Mar 2025
Debt / equity
0.6x
computed by olivLawbalance sheet at 31 Mar 2025
Interest coverage
1.6x
computed by olivLawFY 2025

Liquidity

Current ratio
1.0x
computed by olivLawbalance sheet at 31 Mar 2025
Quick ratio
0.5x
computed by olivLawbalance sheet at 31 Mar 2025
Cash ratio
0.2x
computed by olivLawbalance sheet at 31 Mar 2025

Cash

Operating cash flow
1,057.2 bn JPY
computed by olivLawFY 2025
Capital expenditure
200.8 bn JPY
computed by olivLawFY 2025
Free cash flow
856.4 bn JPY
computed by olivLawFY 2025
FCF conversion
793.5%
computed by olivLawFY 2025
Cash conversion
95.8%
computed by olivLawFY 2025

Efficiency

Days sales outstanding
55 days
computed by olivLawFY 2025 · balance sheet at 31 Mar 2025
Days inventory outstanding
280 days
computed by olivLawFY 2025 · balance sheet at 31 Mar 2025
Days payables outstanding
118 days
computed by olivLawFY 2025 · balance sheet at 31 Mar 2025
Cash conversion cycle
217 days
computed by olivLawFY 2025 · balance sheet at 31 Mar 2025

Market and valuation

Market capitalisation
unavailable
input data missing
Enterprise value
unavailable
input data missing
Market cap / net income TTM
unavailable
input data missing
P/E (TTM)
unavailable
input data missing
Earnings yield
unavailable
input data missing
P/B
unavailable
input data missing
P/S
unavailable
input data missing
EV/EBITDA
unavailable
input data missing
EV/EBIT
unavailable
input data missing
EV/Sales
unavailable
input data missing
P/FCF
unavailable
input data missing
FCF yield
unavailable
input data missing
Dividend yield
unavailable
input data missing
Shareholder yield (distributions)
unavailable
input data missing

1 indicators that do not apply to the sector.

Valuation

olivLaw classification

Unattractive profile

Score: 32 / 100

A scoring methodology on indicators and valuation, not investment advice.

score < 40

Closing price

21.06 USD

04 Nov 2026Source: olivLaw, closing series

Market cap: unavailable

Price and reporting are in different currencies; market indicators are unavailable.

Key indicators

Market capitalisation
unavailable
input data missing
P/E (TTM)
unavailable
input data missing
P/B
unavailable
input data missing
EV/EBITDA
unavailable
input data missing
ROE
1.5%
computed by olivLawFY 2025 · balance sheet at 31 Mar 2025
Net margin
2.4%
computed by olivLawFY 2025
Revenue growth (YoY)
7.5%
computed by olivLawFY 2025
Dividend yield
unavailable
input data missing

Coverage and freshness

35/37 reporting lines present
Latest full fiscal year: 2025
Latest reported period: 31 Mar 2025
Latest balance sheet date: 31 Mar 2025
Share count (cover of the latest filing), as of: 31 Mar 2020
Source: SEC (XBRL)published 25 Jun 2025
verified 286derived 2

The data is older than the freshness threshold.

Score by group

  • Balance sheet15
  • Growth36
  • Returns100
  • Quality32

Estimated value range

unavailable — no valuation assumptions for the reporting currency

Valuation assumptions are editorial choices, not measured; beta is not measured.

Valuation methods

    Multiple comparisons use the SIC vertical

    Classification (SIC) comparables group by industry code, not by economic activity; the direct group is an editorial selection by activity. Members' multiples are on their own trailing twelve months, at their own latest close.

    Assumptions (illustrative, editorial)

    Risk-free rate
    6.5%
    Equity risk premium
    6.0%
    Beta (default)
    1.00
    Cost of equity
    12.5%
    Terminal growth
    3.0%

    Factor scorecard

    Unattractive profile · Score 32/100

    FactorValueScoreWeight used
    ROIC · Quality1.9%0 (on a fixed band)16%
    Net margin · Quality2.4%16 (on a fixed band)10%
    FCF conversion · Quality793.5%100 (on a fixed band)10%
    Revenue CAGR 3Y · Growth8.7%72 (on a fixed band)13%
    EPS CAGR 3Y · Growth-22.8%0 (on a fixed band)13%
    Net debt / EBITDA · Balance sheet3.2x22 (on a fixed band)16%
    Interest coverage · Balance sheet1.6x2 (on a fixed band)10%
    Current ratio · Balance sheet1.0x17 (on a fixed band)6%
    P/E (TTM) · Valuationunavailableunavailable—
    EV/EBITDA · Valuationunavailableunavailable—
    FCF yield · Valuationunavailableunavailable—
    Shareholder yield (distributions) · Returnsunavailableunavailable—
    Payout ratio (FCF) · Returns35.3%100 (on a fixed band)6%

    Factors without a value were dropped; the remaining weights were renormalised.

    Score groups

    • Balance sheet15/100 · 3/3 factors with a value
    • Growth36/100 · 2/2 factors with a value
    • Quality32/100 · 3/3 factors with a value
    • Returns· partial100/100 · 1/2 factors with a value
    • Valuation· partialunavailable · 0/3 factors with a value

    A «partial» group is computed from under half of its weight or from one factor: it is not a full assessment of the group.

    Memo

    Takeda Pharmaceutical Company Limited (TAK). Latest full fiscal year: 2025; data up to 2025-03-31.

    Figures computed from the financial statements: revenue 4,581.6 bn JPY in 2025; YoY growth 7.5%; net margin 2.4%; ROE 1.5%; net debt/EBITDA 3.2x.

    The estimated value range is 1,779.47–2,198.17 JPY per share (median of 1 methods, agreement: single method); assumptions are illustrative. The range is the median of the methods' low, central and high values, not a probability interval.

    olivLaw score 32/100, methodological classification: unattractive profile (score, margin of safety and method agreement together; not a judgement of the right price). Groups assessed only in part: returns, valuation. Not investment advice.

    Text generated deterministically from the figures shown; no language model. Not investment advice.

    What supports the thesis

    • FCF conversion: 793.5%
    • Revenue CAGR 3Y: 8.7%
    • Payout ratio (FCF): 35.3%

    What contradicts it

    • ROIC: 1.9%
    • Net margin: 2.4%
    • EPS CAGR 3Y: -22.8%
    • Net debt / EBITDA: 3.2x
    • Interest coverage: 1.6x
    • Current ratio: 1.0x

    Not assessed (insufficient data or a ratio without meaning): P/E (TTM), EV/EBITDA, FCF yield, Shareholder yield (distributions).

    Versus the vertical median

    Not enough comparable companies with data for an average.

    olivLaw engine forecast

    The world engine ran after the company's latest material disclosure. Probabilities are of TOUCHING a level within the horizon (not closing there) and sit next to the random walk (p_rw), the no-information benchmark.

    The engine has no published run for this company yet.

    Valuation scenarios (editable assumptions)

    Illustrative scenarios

    Scenarios are not available. input data missing

    AI analysis

    AI-generatedAI-generated analysis (Claude) from cited public sources; it may contain errors. Not investment advice. As of 27 Oct 2026 · Model: claude-haiku-5-5.

    Possibly outdated: the newest document it read is from 17 Jun 2026; since then the company filed 6-K (29 Oct 2026), 6-K (14 Sept 2026), 6-K (31 Aug 2026), 6-K (06 Aug 2026), 6-K (30 Jul 2026).

    In brief

    Takeda is a global research-driven biopharmaceutical company focused on gastrointestinal and inflammation, neuroscience, oncology, and plasma-derived therapies. In fiscal 2026 revenue reached 4505.7 billion JPY, and the company is in a transition period, with new launches and late-stage pipeline programs set against loss of exclusivity on important products.

    SWOT

    Strengths

    • The company has a geographically diversified base and a strong plasma-derived immunology portfolio, backed by a large collection network.
    • The R&D engine combines internal resources with external partnerships and covers several therapeutic modalities.
    • Products such as ENTYVIO and TAKHZYRO show solid growth and hold important positions in key markets.

    Weaknesses

    • A significant share of revenue depends on a small number of products, which makes the company sensitive to loss of exclusivity.
    • Operating profit in fiscal 2026 was very small relative to revenue, which points to margin pressure.
    • Exposure to currency fluctuations, given the large share of revenue from outside Japan, can affect reported results.

    Opportunities

    • New launches such as zasocitinib, oveporexton and rusfertide could open new revenue sources.
    • Higher plasma collection volume and network optimization could support growth in immunology products.
    • Digitalization and artificial intelligence could speed up drug discovery and streamline operations.

    Threats

    • Generic and biosimilar competition could further reduce sales of products whose patent protection has expired.
    • Price pressure from insurers and pharmacy benefit managers could limit revenue.
    • Regulatory changes and rising compliance requirements could prolong approvals and increase costs.

    Risks

    • Clinical trial failurehigh

      Drug development is costly and uncertain, and studies can fail even at late stages, which could lead to discontinuation of important programs.

    • Loss of exclusivityhigh

      Patent expiry could quickly reduce sales of key products if new launches do not offset the decline.

    • Pricing pressuremedium

      Price control schemes and mandatory discounts in the U.S. and Europe could affect margins and revenue.

    • Plasma supplymedium

      Plasma-derived production depends on collected raw material, and difficulties in acquisition or delayed approval of new centers could affect output.

    • Regulatory framework and investigationsmedium

      Legislative changes and ongoing investigations could create defense costs, fines or restrictions on reimbursement access.

    Investment thesis

    What would need to be true (bull case)

    • If zasocitinib, oveporexton and rusfertide reach commercial launch, the company could diversify revenue beyond mature products.
    • Growth in plasma-derived immunology products and collection volume could support revenue over the medium term.
    • A diversified portfolio and global presence could cushion the impact of a problem in any single market.

    What would break the thesis

    • Generic competition for important products could reduce revenue faster than new launches can compensate.
    • Operating profit that is very small relative to revenue could limit investment capacity and shareholder returns.
    • If studies or approvals are delayed, expected launches could postpone revenue growth.

    What to watch

    • FDA submission of zasocitinib and any decision on Priority Review2026
    • Trend of sales for products facing generic competition, particularly VYVANSE/ELVANSE and TRINTELLIXQ1 2027
    • Commercial launches of oveporexton and rusfertide after expected approvals2027
    • New reporting structure with New Launches and Core In-line Brands categories starting in fiscal 2027next 10-K

    Products, market & competition

    AI-generatedAI-generated analysis (Claude) from cited public sources; it may contain errors. Not investment advice. As of 27 Oct 2026 · Model: claude-haiku-5-5.

    Possibly outdated: the newest document it read is from 17 Jun 2026; since then the company filed 6-K (29 Oct 2026), 6-K (14 Sept 2026), 6-K (31 Aug 2026), 6-K (06 Aug 2026), 6-K (30 Jul 2026).

    The business

    Takeda describes itself as a global biopharmaceutical company focused on discovering and delivering life-transforming treatments in three core therapeutic areas: gastrointestinal and inflammation, neuroscience and oncology, along with plasma-derived therapies and vaccines 1. The company has a presence in about 80 countries and regions, major research centers in Japan and the United States, and approximately 47000 employees worldwide 1. For the fiscal year ended March 31, 2026, the company operated as a single operating segment and reported operating profit of 6.2 billion JPY 1.

    Its business model combines an internal R&D engine with external partners to access different modalities such as biologics and small molecules 1. The company is pursuing efficiency through digitalization, automation and AI, and in March 2026 its Board approved further steps including streamlining of corporate functions 1. Capital is directed toward investment in the business, maintaining an investment grade credit rating and returning cash to shareholders 1.

    Past acquisitions such as Millennium Pharmaceuticals, Nycomed and Shire extended its presence in oncology, Europe, emerging markets and rare diseases 1. In recent fiscal years the company divested assets in non-core areas and now focuses on strategic pipeline investment, new product launches, efficiency improvements and shareholder returns 1.

    Segments

    Gastrointestinal and inflammation

    The leading product is ENTYVIO, for ulcerative colitis and Crohn's disease, which was the top selling product in fiscal 2026 with revenue of 958.0 billion JPY 1. Other products in this area include GATTEX/REVESTIVE, TAKECAB/VOCINTI and EOHILIA for eosinophilic esophagitis 1.

    Rare diseases and plasma-derived therapies

    TAKHZYRO, for prevention of hereditary angioedema attacks, generated 223.9 billion JPY, while the plasma immunology portfolio including GAMMAGARD LIQUID/KIOVIG, HYQVIA and CUVITRU delivered 790.6 billion JPY 1. This segment depends on a plasma donation network that exceeds 270 centers in the U.S. and EU 1.

    Oncology and neuroscience

    The company reported that zasocitinib, an oral TYK2 inhibitor for psoriasis and other immune-mediated diseases, met its primary endpoints in two Phase 3 studies, with an FDA submission targeted in calendar year 2026 1. The pipeline also includes rusfertide and oveporexton, for which NDAs were submitted in the U.S. with Priority Review granted 1.

    Market context

    Takeda operates in a global medicines market where pricing, reimbursement and generic competition are constant pressures. More than 90 percent of revenue comes from outside Japan, especially the United States, Europe and China 1. The regulatory framework is shifting, and the EU pharmaceutical reform, with potentially shorter exclusivity periods, could change market conditions for new products 1.

    In the U.S. and European markets, distributors and pharmacy benefit managers press on prices, and mandatory discounts under the 340B program and the Inflation Reduction Act could reduce revenue from some products 1. Revenue is also exposed to currency movements, particularly against the U.S. dollar and the euro 1.

    Trends

    • Loss of exclusivity on mature productsheadwind

      Generic competition reduced VYVANSE/ELVANSE sales to 203.2 billion JPY in fiscal 2026, and the company expects these declines to continue in fiscal 2027, and anticipates generic competition for TRINTELLIX after December 2026 1.

    • New launches and pipeline expansiontailwind

      Oveporexton, rusfertide and zasocitinib could be launched commercially in 2026 and 2027, which could offset declines in mature products 1.

    • Growth in plasma collectiontailwind

      Plasma collection volume grew in fiscal 2026, supported by new donation centers and network optimization, which supports the plasma-derived immunology products 1.

    • Currency effects and price pressuremixed

      A weaker yen had a positive effect on revenue in recent years, but a stronger yen could reduce yen-denominated revenue, and drug price pressure remains an issue 1.

    Competitive position

    Takeda competes on efficacy, safety and price, and products under patent protection face generic or biosimilar competition once protection expires 1. The company notes that some of its principal products face considerable competition following expiration of intellectual property protection 1.

    In plasma-derived immunology, rare diseases and gastroenterology, Takeda competes with other companies developing similar or alternative treatments. The provided sources do not name competitors, so the list below is limited to what the filing explicitly mentions 1.

    • Generic and biosimilar manufacturers

      They reduced sales of mature Takeda products such as VYVANSE/ELVANSE and AZILVA after patent protection expired 1.

    • Companies with rival rare disease treatments

      For products such as TAKHZYRO and ELAPRASE, competition depends on efficacy, market access and reimbursement, without a named competitor in the source 1.

    • Plasma immunology competitors

      Plasma collection and fractionation compete with other immunoglobulin producers, as the raw material risks in the filing suggest 1.

    • TYK2 inhibitor developers in psoriasis

      Zasocitinib enters a treatment area where other therapeutic agents exist, but the source does not name direct competitors 1.

    News & filings

    In the press

    Sources

    1. [1] Form 20-F, fiscal year ended 2026-03-31 · SEC / Takeda Pharmaceutical Company Limited · 17 Jun 2026

    Figures computed by olivLaw from SEC filings and closing prices; the qualitative analysis is AI-generated from cited sources. Not investment advice.