olivlawolivlaw

olivLaw · US equity research

GSK plc GSK

Pharmaceutical Preparations · SIC 2834 · Vertical: Pharmaceutical Preparations (SIC 2834)

51.15USD+5.03% · 1 dayClose 04 Nov 2026

GSK plc is a biopharmaceutical company focused on specialty medicines and vaccines, with emphasis on respiratory, immunology, inflammation, oncology and HIV. Sales in fiscal 2025 exceeded £32 billion, and the company is in a leadership transition while accelerating its pipeline, which matters for investor expectations.

The AI analysis may be outdated: new filings came after its sources (see the «AI analysis» section).

At the close of 04 Nov 2026, GSK plc (GSK) stock was 51.15 USD (+5.03% on the day), with beta 0.24, 52-week range 46.11–61.18 USD.

Data as of · AI analysis dated · Source: SEC filings and closing prices, computed by olivLaw.

Market cap
unavailable
shares as of 31 Dec 2025
P/E (TTM)
unavailable
Diluted EPS TTM 1.39 · TTM to 31 Dec 2025
E/P (TTM)
unavailable
TTM to 31 Dec 2025
Dividend yield
unavailable
Beta (2y)
0.24
Volatility (1y) 26%
52-week range
46.1161.18

Price history

Loading chart…

Technical reading

RSI (14)
58.9
strong (55–70)
Bollinger (20, 2)
45.96 – 52.31
in the upper half of the band · %B 0.82 · band width 12.9%
SMA 50 / 200
49.29 / 52.36
mixed trend
MACD (12, 26, 9)
0.24 / 0.16
MACD above signal

Indicators describe past prices; on their own they do not predict direction. On our history the RSI ≤ 40 filter added no return (see the signals methodology).

Performance

CompanyS&P 500vs S&P 500Vertical median
1 month+9.9%−1.1%+11.0 pp—
3 months−0.6%−0.5%−0.2 pp—
6 months+1.2%+4.4%−3.2 pp—
Year to date+4.3%+12.3%−8.0 pp—
1 year+9.2%+13.5%−4.3 pp+19.3%
3 years+48.5%+76.4%−27.9 pp+13.0%
5 years+17.6%+63.7%−46.1 pp—
Max drawdown (1y)
−24.4%
18 Feb 2026 → 13 Oct 2026
Max drawdown (5y)
−38.8%
13 Apr 2022 → 27 Sept 2022
Compound annual growth (5y)
+3.3%
S&P 500 +10.4%

Price returns, dividends excluded.

Quarterly results

ESEF annual reports carry no quarters: the results are annual (below).

E/P over time

the price (USD) and the reports are in different currencies

E/P = trailing-12-month diluted EPS / price at quarter end. E/P is the inverse of P/E and stays defined when earnings are negative.

Fiscal years

Fiscal year20182019202020212022202320242025
Revenue30.8 bn33.8 bn24.4 bn24.7 bn29.3 bn30.3 bn31.4 bn32.7 bn
Revenue YoY+2.1%+9.5%−27.8%+1.4%+18.7%+3.4%+3.5%+4.1%
Net income3.6 bn4.6 bn5.7 bn4.4 bn15.0 bn4.9 bn2.6 bn5.7 bn
Net income YoY+136.5%+28.2%+23.8%−23.7%+241.1%−67.1%−47.7%+122.0%
Diluted EPS0.730.931.431.083.661.200.621.39
Diluted EPS YoY+135.2%+27.0%+54.0%−24.1%+238.4%−67.3%−48.1%+123.2%
net %11.8%13.8%23.6%17.8%51.0%16.2%8.2%17.5%
Free cash flow7.1 bn6.8 bn7.5 bn7.0 bn6.3 bn5.5 bn5.2 bn6.4 bn

Reported results vs expectations

Loading…

Balance sheet & financial health

Fiscal year 2025 · 31 Dec 2025

Cash
3.4 bn GBP
Financial debt
17.7 bn GBP
Net debt
14.3 bn GBP
Equity
16.0 bn GBP
Total assets
61.1 bn GBP
Debt / equity
1.11x
Current ratio
0.82x
ROE
39.4%
ROA
9.5%
FCF margin
19.6%

Financial statements (source on every figure)

Revenue and net income (GBP)

Margins

Income statement · GBP

Revenue
2023
30.3 bn
2024
31.4 bn
2025
32.7 bn

SEC (XBRL)· 06 Mar 2026verified

Cost of revenue
2023
8.6 bn
2024
9.0 bn
2025
9.0 bn

SEC (XBRL)· 06 Mar 2026verified

Gross profit
2023
21.8 bn
2024
22.3 bn
2025
23.7 bn

SEC (XBRL)· 06 Mar 2026verified

Research & development
2023
6.2 bn
2024
6.4 bn
2025
7.5 bn

SEC (XBRL)· 06 Mar 2026verified

Operating income
2023
6.7 bn
2024
4.0 bn
2025
7.9 bn

SEC (XBRL)· 06 Mar 2026verified

Depreciation & amortisation
2023
2.3 bn
2024
2.6 bn
2025
2.3 bn

SEC (XBRL)· 06 Mar 2026verified

EBITDA
2023
9.0 bn ≈
2024
6.6 bn ≈
2025
10.2 bn ≈

SEC (XBRL)· 06 Mar 2026derived

Interest expense
2023
792.0 m
2024
669.0 m
2025
701.0 m

SEC (XBRL)· 06 Mar 2026verified

Pre-tax income
2023
6.1 bn
2024
3.5 bn
2025
7.4 bn

SEC (XBRL)· 06 Mar 2026verified

Income tax
2023
756.0 m
2024
526.0 m
2025
1.1 bn

SEC (XBRL)· 06 Mar 2026verified

Net income
2023
4.9 bn
2024
2.6 bn
2025
5.7 bn

SEC (XBRL)· 06 Mar 2026verified

Diluted EPS
2023
1.20
2024
0.62
2025
1.39

SEC (XBRL)· 06 Mar 2026verified

Weighted average diluted shares
2023
4.1 bn
2024
4.1 bn
2025
4.1 bn

SEC (XBRL)· 06 Mar 2026verified

Balance sheet · GBP

Cash
2023
2.9 bn
2024
3.9 bn
2025
3.4 bn

SEC (XBRL)· 06 Mar 2026verified

Receivables
2023
7.4 bn
2024
6.8 bn
2025
7.5 bn

SEC (XBRL)· 06 Mar 2026verified

Inventories
2023
5.5 bn
2024
5.7 bn
2025
5.9 bn

SEC (XBRL)· 06 Mar 2026verified

Current assets
2023
18.6 bn
2024
17.0 bn
2025
17.5 bn

SEC (XBRL)· 06 Mar 2026verified

Property, plant & equipment, net
2023
9.0 bn
2024
9.2 bn
2025
9.3 bn

SEC (XBRL)· 06 Mar 2026verified

Goodwill
2023
6.8 bn
2024
7.0 bn
2025
7.0 bn

SEC (XBRL)· 06 Mar 2026verified

Intangibles (excl. goodwill)
2023
14.8 bn
2024
15.5 bn
2025
16.7 bn

SEC (XBRL)· 06 Mar 2026verified

Total assets
2023
59.0 bn
2024
59.5 bn
2025
61.1 bn

SEC (XBRL)· 06 Mar 2026verified

Accounts payable
2023
15.8 bn
2024
15.3 bn
2025
15.4 bn

SEC (XBRL)· 06 Mar 2026verified

Short-term debt
2023
2.8 bn
2024
2.3 bn
2025
3.0 bn

SEC (XBRL)· 06 Mar 2026verified

Long-term debt
2023
15.2 bn
2024
14.6 bn
2025
14.7 bn

SEC (XBRL)· 06 Mar 2026verified

Current liabilities
2023
21.1 bn
2024
21.7 bn
2025
21.4 bn

SEC (XBRL)· 06 Mar 2026verified

Total liabilities
2023
46.2 bn
2024
46.4 bn
2025
45.2 bn

SEC (XBRL)· 06 Mar 2026verified

Equity
2023
12.8 bn
2024
13.1 bn
2025
16.0 bn

SEC (XBRL)· 06 Mar 2026verified

Shares outstanding at year end
2023
4.3 bn
2024
4.3 bn
2025
4.3 bn

SEC (XBRL)· 06 Mar 2026verified

Cash flow · GBP

Operating cash flow
2023
6.8 bn
2024
6.6 bn
2025
7.7 bn

SEC (XBRL)· 06 Mar 2026verified

Capex
2023
1.3 bn
2024
1.4 bn
2025
1.3 bn

SEC (XBRL)· 06 Mar 2026verified

Free cash flow
2023
5.5 bn ≈
2024
5.2 bn ≈
2025
6.4 bn ≈

SEC (XBRL)· 06 Mar 2026derived

Investing cash flow
2023
-1.6 bn
2024
-1.2 bn
2025
-4.2 bn

SEC (XBRL)· 06 Mar 2026verified

Financing cash flow
2023
-5.6 bn
2024
-4.7 bn
2025
-3.7 bn

SEC (XBRL)· 06 Mar 2026verified

Share repurchases
2023
0
2024
0
2025
1.4 bn

SEC (XBRL)· 06 Mar 2026verified

Computed indicators

Growth

Revenue growth (YoY)
4.1%
computed by olivLawFY 2025
Revenue CAGR 3Y
3.7%
computed by olivLawFY 2022 → FY 2025
Revenue CAGR 5Y
6.0%
computed by olivLawFY 2020 → FY 2025
EBIT growth (YoY)
97.3%
computed by olivLawFY 2025
Net income growth (YoY)
122.0%
computed by olivLawFY 2025
Net income CAGR 3Y
-27.4%
computed by olivLawFY 2022 → FY 2025
Net income CAGR 5Y
-0.1%
computed by olivLawFY 2020 → FY 2025
EPS growth (YoY)
123.2%
computed by olivLawFY 2025
EPS CAGR 3Y
-27.6%
computed by olivLawFY 2022 → FY 2025
EPS CAGR 5Y
-0.5%
computed by olivLawFY 2020 → FY 2025
FCF growth (YoY)
24.0%
computed by olivLawFY 2025

Profitability

Gross margin
72.4%
computed by olivLawFY 2025
EBITDA margin
31.4%
computed by olivLawFY 2025
EBIT margin
24.3%
computed by olivLawFY 2025
Net margin
17.5%
computed by olivLawFY 2025
FCF margin
19.6%
computed by olivLawFY 2025

Returns

ROE
38.0%
computed by olivLawFY 2025 · balance sheet at 31 Dec 2025
ROA
9.5%
computed by olivLawFY 2025 · balance sheet at 31 Dec 2025
ROIC
23.9%
computed by olivLawFY 2025 · balance sheet at 31 Dec 2025
ROCE
20.0%
computed by olivLawFY 2025 · balance sheet at 31 Dec 2025
Payout ratio (EPS)
unavailable
input data missing
Payout ratio (FCF)
unavailable
input data missing

Balance sheet

Net debt
14.3 bn GBP
computed by olivLawbalance sheet at 31 Dec 2025
Net debt / EBITDA
1.4x
computed by olivLawFY 2025 · balance sheet at 31 Dec 2025
Debt / equity
1.1x
computed by olivLawbalance sheet at 31 Dec 2025
Interest coverage
11.3x
computed by olivLawFY 2025

Liquidity

Current ratio
0.8x
computed by olivLawbalance sheet at 31 Dec 2025
Quick ratio
0.5x
computed by olivLawbalance sheet at 31 Dec 2025
Cash ratio
0.2x
computed by olivLawbalance sheet at 31 Dec 2025

Cash

Operating cash flow
7.7 bn GBP
computed by olivLawFY 2025
Capital expenditure
1.3 bn GBP
computed by olivLawFY 2025
Free cash flow
6.4 bn GBP
computed by olivLawFY 2025
FCF conversion
111.8%
computed by olivLawFY 2025
Cash conversion
75.6%
computed by olivLawFY 2025

Efficiency

Days sales outstanding
80 days
computed by olivLawFY 2025 · balance sheet at 31 Dec 2025
Days inventory outstanding
235 days
computed by olivLawFY 2025 · balance sheet at 31 Dec 2025
Days payables outstanding
622 days
computed by olivLawFY 2025 · balance sheet at 31 Dec 2025
Cash conversion cycle
-307 days
computed by olivLawFY 2025 · balance sheet at 31 Dec 2025

Market and valuation

Market capitalisation
unavailable
input data missing
Enterprise value
unavailable
input data missing
Market cap / net income TTM
unavailable
input data missing
P/E (TTM)
unavailable
input data missing
Earnings yield
unavailable
input data missing
P/B
unavailable
input data missing
P/S
unavailable
input data missing
EV/EBITDA
unavailable
input data missing
EV/EBIT
unavailable
input data missing
EV/Sales
unavailable
input data missing
P/FCF
unavailable
input data missing
FCF yield
unavailable
input data missing
Dividend yield
unavailable
input data missing
Shareholder yield (distributions)
unavailable
input data missing

1 indicators that do not apply to the sector.

Valuation

olivLaw classification

Neutral profile

Score: 55 / 100

A scoring methodology on indicators and valuation, not investment advice.

Closing price

51.15 USD

04 Nov 2026Source: olivLaw, closing series

Market cap: unavailable

Price and reporting are in different currencies; market indicators are unavailable.

Key indicators

Market capitalisation
unavailable
input data missing
P/E (TTM)
unavailable
input data missing
P/B
unavailable
input data missing
EV/EBITDA
unavailable
input data missing
ROE
38.0%
computed by olivLawFY 2025 · balance sheet at 31 Dec 2025
Net margin
17.5%
computed by olivLawFY 2025
Revenue growth (YoY)
4.1%
computed by olivLawFY 2025
Dividend yield
unavailable
input data missing

Coverage and freshness

34/37 reporting lines present
Latest full fiscal year: 2025
Latest reported period: 31 Dec 2025
Latest balance sheet date: 31 Dec 2025
Share count (cover of the latest filing), as of: 31 Dec 2025
Source: SEC (XBRL)published 06 Mar 2026
verified 369derived 1

Score by group

  • Balance sheet52
  • Growth15
  • Quality88

Estimated value range

unavailable — no valuation assumptions for the reporting currency

Valuation assumptions are editorial choices, not measured; beta is not measured.

Valuation methods

    Multiple comparisons use the SIC vertical: Pharmaceutical Preparations (SIC 2834)

    Classification (SIC) comparables group by industry code, not by economic activity; the direct group is an editorial selection by activity. Members' multiples are on their own trailing twelve months, at their own latest close.

    Assumptions (illustrative, editorial)

    Risk-free rate
    6.5%
    Equity risk premium
    6.0%
    Beta (default)
    1.00
    Cost of equity
    12.5%
    Terminal growth
    3.0%

    Factor scorecard

    Neutral profile · Score 55/100

    FactorValueScoreWeight used
    ROIC · Quality23.9%92 (vs peers)17%
    Net margin · Quality17.5%68 (vs peers)10%
    FCF conversion · Quality111.8%100 (on a fixed band)10%
    Revenue CAGR 3Y · Growth3.7%31 (on a fixed band)14%
    EPS CAGR 3Y · Growth-27.6%0 (on a fixed band)14%
    Net debt / EBITDA · Balance sheet1.4x43 (vs peers)17%
    Interest coverage · Balance sheet11.3x100 (on a fixed band)10%
    Current ratio · Balance sheet0.8x2 (on a fixed band)7%
    P/E (TTM) · Valuationunavailableunavailable—
    EV/EBITDA · Valuationunavailableunavailable—
    FCF yield · Valuationunavailableunavailable—
    Shareholder yield (distributions) · Returnsunavailableunavailable—
    Payout ratio (FCF) · Returnsunavailableunavailable—

    Factors without a value were dropped; the remaining weights were renormalised.

    Score groups

    • Balance sheet52/100 · 3/3 factors with a value
    • Growth15/100 · 2/2 factors with a value
    • Quality88/100 · 3/3 factors with a value
    • Returns· partialunavailable · 0/2 factors with a value
    • Valuation· partialunavailable · 0/3 factors with a value

    A «partial» group is computed from under half of its weight or from one factor: it is not a full assessment of the group.

    Memo

    GSK plc (GSK). Latest full fiscal year: 2025; data up to 2025-12-31.

    Figures computed from the financial statements: revenue 32.7 bn GBP in 2025; YoY growth 4.1%; net margin 17.5%; ROE 38.0%; net debt/EBITDA 1.4x.

    The estimated value range is 22.33–55.49 GBP per share (median of 2 methods, agreement: same basis (multiples on one peer group, not independent confirmations)); assumptions are illustrative. The range is the median of the methods' low, central and high values, not a probability interval.

    olivLaw score 55/100, methodological classification: neutral profile (score, margin of safety and method agreement together; not a judgement of the right price). Groups assessed only in part: returns, valuation. Not investment advice.

    Text generated deterministically from the figures shown; no language model. Not investment advice.

    What supports the thesis

    • ROIC: 23.9%
    • FCF conversion: 111.8%
    • Interest coverage: 11.3x

    What contradicts it

    • EPS CAGR 3Y: -27.6%
    • Current ratio: 0.8x

    Not assessed (insufficient data or a ratio without meaning): P/E (TTM), EV/EBITDA, FCF yield, Shareholder yield (distributions), Payout ratio (FCF).

    Versus the vertical median

    Pharmaceutical Preparations (SIC 2834) · same industry (4-digit SIC) · compared with 39 companies

    Multiples and returns vs the median

    P/E
    —
    vertical median 38.6x
    EV/EBITDA
    —
    vertical median 25.4x
    P/S
    —
    vertical median 7.3x
    P/B
    —
    vertical median 6.1x
    ROE
    38.0%
    vertical median -9.5%
    above median
    Net margin
    17.5%
    vertical median 3.6%
    above median (+382.7%)
    EBIT margin
    24.3%
    vertical median -4.2%
    above median
    Revenue YoY
    4.1%
    vertical median 5.9%
    below median (−29.8%)
    Net debt/EBITDA
    1.4x
    vertical median -0.0x
    above median
    Dividend yield
    —
    vertical median 2.2%

    Price rebased to 100 (monthly, 5 years)

    Companies in the vertical

    Market capP/EROENet marginRevenue YoY1A / 3A
    LLYEli Lilly And Company1,334.0 bn46.086.1%31.9%+44.7%+32% / +140%
    JNJJohnson & Johnson665.2 bn41.920.0%16.2%+6.0%+34% / +79%
    ONCBeone Medicines Ltd.558.4 bn869.914.7%10.7%+40.2%+11% / +102%
    ABBVAbbVie Inc.521.1 bn50.7—15.7%+8.6%+29% / +107%
    MRKMerck & Co., Inc.370.7 bn154.75.1%3.6%+1.3%+43% / +47%
    ABTAbbott Laboratories200.1 bn43.09.2%9.7%+5.7%−10% / +11%
    PFEPfizer Inc175.5 bn43.94.4%6.3%−1.6%+20% / +1%
    VRTXVertex Pharmaceuticals Inc139.2 bn35.320.8%30.7%+8.9%+27% / +55%
    BMYBristol-Myers Squibb Company131.2 bn14.244.1%18.5%−0.2%+30% / +30%
    TEVATeva Pharmaceutical Industries Limited48.8 bn97.46.6%3.6%+4.3%+56% / +326%
    ZTSZoetis Inc.36.9 bn14.764.4%27.5%+2.3%−30% / −50%
    ROIVRoivant Sciences Ltd.27.6 bn—-6.2%-3,535.0%−71.6%+84% / +300%
    RPRXRoyalty Pharma plc26.2 bn47.76.9%25.7%+5.1%+69% / +150%
    UTHRUnited Therapeutics Corporation25.9 bn23.019.1%38.6%+10.6%+25% / +154%
    INSMInsmed Inc24.1 bn—-72.5%-39.9%+66.7%−47% / +340%
    VTRSViatris Inc.22.1 bn—-23.6%-23.9%−3.0%+80% / +109%
    ALNYAlnylam Pharmaceuticals, Inc.21.6 bn8.1126.6%52.8%+65.2%−64% / −4%
    TGTXTg Therapeutics, Inc.9.4 bn22.5100.3%55.2%+87.3%+85% / +381%
    BLRXBioLineRx Ltd4.9 bn—-12.8%-171.7%−95.9%−46% / −97%
    BHCBausch Health Companies Inc.3.1 bn——-7.6%+6.7%+31% / +17%
    ANABAnaptysbio, Inc.1.4 bn11.5—82.4%+157.0%+71% / +404%
    KURAKura Oncology, Inc.677.0 m—-167.7%-384.3%+25.2%−37% / −21%
    DMACDiaMedica Therapeutics Inc.580.8 m—-114.6%—unavailable+25% / +341%
    PHATPhathom Pharmaceuticals, Inc.461.7 m——-30.2%+216.9%−64% / −19%
    ALTAltimmune, Inc.412.4 m—-28.9%-223,804.9%+105.0%−60% / −33%

    1- and 3-year price returns: for GSK from daily closes (the same as the performance table), for the other companies from month-end closes.

    olivLaw engine forecast

    The world engine ran after the company's latest material disclosure. Probabilities are of TOUCHING a level within the horizon (not closing there) and sit next to the random walk (p_rw), the no-information benchmark.

    The engine has no published run for this company yet.

    Valuation scenarios (editable assumptions)

    Illustrative scenarios

    Scenarios are not available. input data missing

    AI analysis

    AI-generatedAI-generated analysis (Claude) from cited public sources; it may contain errors. Not investment advice. As of 27 Oct 2026 · Model: claude-haiku-5-5.

    Possibly outdated: the newest document it read is from 06 Mar 2026; since then the company filed 6-K (02 Nov 2026), 6-K (28 Oct 2026), 6-K (26 Oct 2026).

    In brief

    GSK plc is a biopharmaceutical company focused on specialty medicines and vaccines, with emphasis on respiratory, immunology, inflammation, oncology and HIV. Sales in fiscal 2025 exceeded £32 billion, and the company is in a leadership transition while accelerating its pipeline, which matters for investor expectations.

    SWOT

    Strengths

    • A strong specialty medicines portfolio with accelerated growth and a pipeline strengthened through acquisitions and partnerships.
    • Long-standing expertise in the science of the immune system, particularly in respiratory and inflammation.
    • Strong cash generation that supports R&D investment and shareholder returns.

    Weaknesses

    • Dependence on a limited number of key products and the expiry of exclusivity for important molecules.
    • Long-term weak share price performance, which management acknowledges as significant.
    • The General Medicines segment is declining, which weighs on the overall growth profile.

    Opportunities

    • New launches in oncology and respiratory could open significant growth if they are confirmed in clinical practice.
    • Technology and AI could accelerate discovery and reduce R&D costs if integrated at scale.
    • Development of therapies for fibrotic diseases of the lung, liver and kidney could extend addressable markets.

    Threats

    • Continued pricing pressure in the US and Europe could reduce long-term margins.
    • Trade tensions and possible tariffs on pharmaceutical imports could raise production costs.
    • Competition from licensed assets from China could intensify rivalry in key indications.

    Risks

    • Loss of exclusivityhigh

      The expiry of exclusivity for dolutegravir could significantly reduce revenues if not offset by new launches.

    • Pricing pressurehigh

      Pricing agreements with governments, particularly the US Administration, could limit revenues in key markets.

    • Clinical trial failuremedium

      Negative results in late-stage programmes could affect pipeline value and growth plans.

    • Trade and supply chain risksmedium

      Tariff measures and supply chain reconfiguration could increase costs and disrupt deliveries.

    • AI and data riskslow

      Use of data and AI may raise privacy, security and trust concerns with reputational impact.

    Investment thesis

    What would need to be true (bull case)

    • Strong growth in specialty medicines and a strengthened pipeline could support sustainable growth if new launches are executed well.
    • Solid cash generation and a recovering dividend suggest the investment and shareholder return plan can be funded.
    • Expertise in immune system science and use of technology could improve R&D efficiency and reduce project risk.

    What would break the thesis

    • Continued US pricing pressure and tariff risk could limit margins even if sales grow.
    • The expiry of exclusivity for a major product could create a revenue gap that is hard to fill quickly.
    • Long-term weak share price performance suggests the market may be sceptical about strategy execution.

    What to watch

    • Performance of new launches in respiratory and oncology2026
    • Impact of the US Administration pricing agreement on sales2026
    • Progress of late-stage pipeline and pivotal readouts2026
    • Pace of acquisitions and development agreementsnext 10-K

    Products, market & competition

    AI-generatedAI-generated analysis (Claude) from cited public sources; it may contain errors. Not investment advice. As of 27 Oct 2026 · Model: claude-haiku-5-5.

    Possibly outdated: the newest document it read is from 06 Mar 2026; since then the company filed 6-K (02 Nov 2026), 6-K (28 Oct 2026), 6-K (26 Oct 2026).

    The business

    According to its 2025 annual report filed with the SEC, GSK describes its strategy as a focused biopharma company following the Haleon demerger in 2022, which allowed a reset balance sheet for investment in innovation. Total sales grew to more than £32 billion in 2025 1, and total R&D expense reached £7.5 billion 1. The company reports five major product approvals in 2025 1.

    The company has a portfolio across specialty medicines, vaccines and general medicines. A new CEO, Luke Miels, took over, and stated priorities include executing new launches, accelerating late-stage assets and using technology, including AI, in R&D and manufacturing 1.

    The long-term strategy targets growth ambitions for 2031 and addresses the loss of dolutegravir exclusivity. The pipeline has been strengthened through acquisitions and partnerships, notably in RI&I and oncology, and 58 assets are in the pipeline 1.

    Segments

    Specialty Medicines

    Specialty Medicines sales grew 14% AER and 17% CER in 2025, with double-digit growth in oncology, respiratory, immunology and inflammation, and HIV 1. The segment is the main growth driver.

    Vaccines and General Medicines

    Vaccines sales were stable at AER and up at CER, while General Medicines declined, showing different dynamics between the two lines 1.

    Research and Development

    R&D is organised around four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases. The company began six phase I programmes and had seven positive phase III readouts in 2025 1.

    Market context

    The global medicine market is expected to reach about $2.4 trillion by 2029 1. Specialty medicines' share of global spending is projected to rise significantly, which supports the company's strategy. Pricing pressure in the US and trade uncertainty could however affect margins.

    The regulatory and pricing environment remains dynamic: in December 2025 the company reached a pricing agreement with the US Administration, and tariff policies and supply chain decisions could change market conditions.

    Trends

    • Pricing pressureheadwind

      The US Administration is seeking to lower drug prices by tying them to international levels, which could reduce revenues in the US market if the pressure extends.

    • Burden of chronic diseasetailwind

      Chronic diseases, cancer and respiratory conditions are projected to remain among the top disease burdens, supporting demand for the company's therapies.

    • Artificial intelligence in R&Dmixed

      AI could accelerate drug discovery and development, but realising these benefits depends on talent and public trust in how data is used.

    • Trade tensions and supply chainsmixed

      Tariff policies and reshoring of production in the US and EU could add costs, though a stable zero-tariff arrangement for UK-made products offers some predictability.

    Competitive position

    The source material points to competition from companies developing therapies in the same areas, especially oncology and respiratory, where innovation is rapid. Chinese licensing activity has grown significantly, which could intensify competition for new molecules.

    The company aims to compete through best-in-class or first-in-class medicines, saying over 75% of its assets have this potential, but success depends on clinical results and launch execution.

    • Chinese biopharma companies with licensed assets

      Chinese assets make up a growing share of licensing deals and such companies could compete directly in the same indications.

    • Hengrui Pharma

      Hengrui is named as a partner in a multi-medicine agreement in RI&I and oncology, and therefore also a competitor in the same areas.

    • Companies with anti-IL-5 and asthma therapies

      The company markets treatments for asthma and COPD, a market in which other pharmaceutical companies hold competing products.

    • Developers of liver and metabolic therapies

      Companies working on liver disease and MASH compete for the company's hepatology pipeline assets.

    News & filings

    Figures computed by olivLaw from SEC filings and closing prices; the qualitative analysis is AI-generated from cited sources. Not investment advice.

    GSK plc (GSK): stock, results, valuation and forecast · olivLaw